Universität Mainz
 
Institut für Pharmazie
 
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Univ.-Prof. Dr. G. Dannhardt
AK-Mitglieder
Entzündung
Oxidativer Streß
Muscarin-Rezeptor
NMDA-Rezeptor
Antikonvulsiva
Alkaloide
Angiogenese
 
IAK-PET
 
Dissertationen
 
2004
1993-2003
 
 
 

Arbeitskreis

Prof. Dr. G. Dannhardt

 
 
NMDA-Rezeptor-Agonisten und -Antagonisten

 
 

Veröffentlichungen zum Thema:

Piel, M., Schirrmacher, R., Höhnemann, S., Hamkens, W., Kohl, B.K., Jansen, M., Schmitt, U., Lüddens, H., Dannhardt, G., Rösch, F.:
Synthesis and evaluation of 5,7-dichloro-4-(3-{4-[4-(2-[18F]fluoroethyl)-
piperazin-1-yl]-phenyl}-ureido)-1,2,3,4-tetrahydroquinoline-2-carboxylic acid as a potential NMDA ligand to study glutamatergic neurotransmission in vivo, J. Label Compd Radiopharm 2003, 46; 645-659

Jansen, M.; Potschka, H.; Brandt, C.; Dannhardt, G.; Löscher, W. Hydantoin substituted 4,6-dichloroindole-2-carboxylic Acids as Ligands with high affinity for the Glycine Binding Site of the NMDA Receptor, J. Med. Chem. 2003, 46; 64-73

Kohl, B.K.; Dannhardt, G.: The NMDA Receptor Complex: A Promising Target for Novel Antiepileptic Strategies, Curr. Med. Chem. 2001; 8; 1275-1289

Dannhardt, G.; Kohl, B.K.; Benzimidazoles as ligands for the glycine-site of the NMDA receptor: Synthesis, radioligand and binding-studies and structure-activity relationships, Pharm. Pharmacol. Lett. 2000; 10; 1-4

Dannhardt, G.; von Gruchalla, M.; Kohl, B.K.; Parsons, C.G.: A Novel Series of 2-Carboxytetrahydroquinolines provides New Insights into the Eastern Region of Glycine Site NMDA Antagonists, Arch. Pharm. Pharm. Med. Chem. 2000; 333; 267-274

Dannhardt, G.; v. Gruchalla, M.; Herkert, M.: Tools for NMDA-receptor elucidation: Synthesis and binding affinities of (+)-MK-801 derivatives designed for detection and purification of the receptor protein. Pharm. Pharmacol. Lett. 1998; 8; 11-15

Dannhardt, G.; Kohl, B. K.; The gylcine site on the NMDA receptor: structure-activity relationships and possible therapeutic applications. Curr. Med. Chem. 1998; 5; 253-263

Dannhardt, G.; v. Gruchalla, M.; Elben, U.: Tools for NMDA-receptor elucidation: Synthesis of spacer-coupled MK-801 derivatives. Pharrn. Pharmacol. Lett. 1994; 12-15

Dannhardt, G.; v. Gruchalla, M.; Elben, U; Herkert, M.: Tools for NMDA-receptor elucidation: Binding affinities of spacer-coupled MK-801 derivatives. Pharm. Pharmacol. Lett. 1994; 16-18

 
Zuletzt geändert am 10. Mai 2003 von Michaela Jansen
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